Somatic Cells vs Gametes

Somatic Cells vs Gametes – detailed comparison:

Somatic Cells

A somatic cell is any cell that makes up an organism, with the exception of a reproductive cell. The word ”somatic” is derived from the Greek word ”soma” which means ”body.”

Basically, these cells are found pretty much everywhere in the human body as they are the cells that replace old ones, repair damage, as well as contribute to development and growth.


Blood Cells

A blood cell, also known as a hematopoietic cell or hemocyte, is a cell that is produced through hematopoiesis. It is found mainly in the blood.

The main types of blood cells include:

Platelets (thrombocytes)

Platelets, also referred to as thrombocytes, are colorless, nonnucleated blood components that are essential in the formation of blood clots. They are found only in the blood of mammals.

They help the blood clotting process by gathering at the site of an injury or a wound, attaching to the lining of the injured blood vessel, and creating a base on which blood coagulation can happen.

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White Blood Cells (leukocytes)

White blood cells, also referred to as leukocytes, are cellular components of the blood that lack hemoglobin.

Furthermore, they have a nucleus and can defend the human body against disease and infection by destroying infectious agents and cancer cells, ingesting cellular debris and foreign materials, or by producing antibodies.

Types of white blood cells include:

  • eosinophils – these cells destroy cancer cells, attack and kill parasites, and help with allergic responses;
  • basophils – these white cells are rare and are involved in allergic inflammatory reactions since they contain histamine (a neurotransmitter that controls the body’s immune response) and heparin (an anticoagulant);
  • neutrophils – they are your first line of defense when infection strikes and the most numerous type of white blood cells. These cells kill and digest fungi and bacteria;
  • lymphocytes – these cells create antibodies to defend against viruses, bacteria, and other harmful invaders;
  • monocytes – they help to break down harmful bacteria and have a longer lifespan than many white blood cells.

Red Blood Cells (erythrocytes)

They account for about 43% of the blood. Every second, 4 million new red blood cells are produced in the human body. Unlike other cells of the human body, mature erythrocytes do not contain mitochondria, nucleus, or ribosomes.

These cells remove carbon dioxide from the body, carrying it to the lungs to be exhaled. Hemoglobin is the protein inside erythrocytes that transports oxygen. Hemoglobin is made up of 4 protein molecules that are connected together.

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Muscle Cells

A muscle cell, also referred to as a myocyte, is a specialized cell that can shorten its length using several motor proteins specially arranged within the cell.

There are a few specialized forms of muscle cells, including cardiac, skeletal, and smooth muscle cells, with various properties.

  • smooth muscle cells – they are responsible for involuntary movements, such as the movement of the intestines during peristalsis;
  • skeletal muscle cells – they make up the muscle tissues connected to the skeleton and are essential in locomotion;
  • cardiac muscle cells – they are the muscle fibers that comprise the myocardium, a working muscle that requires a non-stop supply of nutrients and oxygen to function efficiently.

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Bone Cells

There are special types of cells that are found only in the bone. They include 4 types of bone cells:

Lining Cells

They protect the bone from chemicals in the blood which dissolves crystals (like – pyrophosphate). Furthermore, they are responsible for the immediate release of calcium from the bone if the blood calcium is too low. Also, these bone cells are former osteoblasts that have become flat and line the entire surface of the bone.


They sense mechanical strain on the bone and can secrete growth factors to stimulate the osteoblasts or activate the lining cells. They have long branches that allow them to contact each other as well as the lining cells on the bone surface. These are actually the bone cells that live inside the bone.


These cells are derived from marrow stromal cells by differentiation of pre-osteoblasts. They are cuboidal mononuclear bone cells 15 to 30 µm in length, that form a contiguous monolayer over the surface of the bone.


They are a large multinucleate giant bone cell that is attached to the bone surface. An osteoclast has 15 to 20 nuclei and may measure a few hundreds of micrometers across. Moreover, osteoclasts are equipped with phagocytic-like mechanisms similar to circulating macrophages.

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Neurons are nerve cells whose main function is to transmit signals from the body to the brain via chemical and electrical signaling.

It is estimated that there are over 86 billion neurons in the brain. To reach this target, an unborn baby must create approximately 250,000 nerve cells per minute.

A typical nerve cell has:

  • a single axon (an extra-long, branched cellular filament, that may be thousands of times the length of the soma);
  • dendrites (feathery filaments which are attached to the cell body in a complex branching dendritic tree);
  • a soma (the bulbous cell body that contains the cell nucleus).


Gametes, also known as sex cells, are an organism’s reproductive cells. They are produced in the gonads. In males, this is called spermatogenesis, while in females, it is called oogenesis.

The female gamete is called an egg. It is not made to move and is much larger than the sperm. Once the egg is released from the ovary during ovulation, it goes into the fallopian tube.

The male gamete is called sperm. It has a long tail, flagellum, which allows it to move towards the female egg. It can melt the surface of the female egg by releasing enzymes to dissolve the outer membrane of the egg. It is much smaller than the female egg and very mobile.

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Bottom Line – Somatic Cells vs Gametes

Gametes are reproductive cells that unite during sexual reproduction to form a new cell called a zygote. Somatic cells are any cell in the human body that is not germ cells (cells that go on to become gametes), gametes (egg or sperm), or stem cells.

The main difference between a gamete and a somatic cell is that a somatic cell is just meant to create a body and support life, and it can never help in the reproductive process.

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