NeuroCore vs C4

NeuroCore vs C4 – Which Is The Best Pre-Workout Supplement?

MuscleTech Neurocore

MuscleTech NeuroCore is a pre-workout supplement that claims to promote:

  • endurance;
  • energy;
  • performance;
  • cognition;
  • focus.

It has been blended into a perfect formula, and the mixture of ingredients works in the following ways: it contains 330 milligrams of pure caffeine (per 3 scoops) that deliver a rush of energy to improve your performance and workout.


Caffeine Anhydrous

Caffeine is a mild central nervous system stimulant that is found in a lot of things we drink, from tea or coffee to soda and energy drinks, as well as in chocolate.

Creatine Hydrochloride

Creatine is a natural supplement that is used to boost athletic performance. Creatine also allows you to produce more adenosine triphosphate (the molecular unit of currency of intracellular energy transfer) energy to fuel your muscles during high-intensity exercise.


It is an amino acid that is present almost solely in the green tea plant (Camellia sinensis, and certain other species of Camellia). Moderate levels of L-theanine and caffeine helped a group of young adults to focus better during demanding tasks, during a 2013 study which was published in NCBI.


This supplement contains 3000mg of L-citrulline, an amino acid that is usually produced by the body. The body converts this amino acid to L-arginine, another type of amino acid that may increase blood flow by increasing nitric oxide production.

Moreover, L-citrulline may produce positive effects on muscles by decreasing amino acid breakdown and stimulating protein synthesis.

Rhodiola Rosea

Rhodiola is an herb that grows in the cold, mountainous regions of Asia and Europe. This herb has long been known as a natural substance that increases the human body’s resistance to stress in non-specific ways.


It is a popular supplement among fitness enthusiasts and professional athletes. Together with histidine, beta-alanine produces carnosine, a natural antioxidant, and a non-enzymatic free radical scavenger.

Carnosine also reduces lactic acid accumulation in the muscles during physical exercise, leading to improved athletic performance.


It is an evergreen tree that grows in western Africa in Cameroon, Nigeria, Gabon, and Congo.

Because it blocks an enzyme called monoamine oxidase, Yohimbe has been promoted as a herbal remedy for depression. Additionally, Yohimbe has been found to increase lipolysis by blocking alpha-2 receptor activation and increasing the release of norepinephrine available to fat cells.


Some of its advantages include:

  • easy to take;
  • intense and better focus;
  • long-lasting muscle gains and pumps;
  • enhanced muscle growth;
  • amplified strength.

Side Effects

Most of its side effects come from its high content of caffeine, which is currently the world’s most commonly used drug.

Stimulant drugs work partly by stimulating the sympathetic nervous system, which causes the same physical effects as the “fight or flight response” – making you feel more alert, speeding up the breathing and heart, and increasing muscle tension.

A moderate intake of caffeine may lead to jitteriness and nervousness in caffeine-sensitive individuals.

Moreover, caffeine increases the amount of acid in the stomach and may cause an upset stomach or heartburn. It can also lead to an increase in urination shortly after having caffeine.

Cellucor C4

Cellucor claims that C4 is the number #1 performance and energy booster used by bodybuilders and athletes. C4 is actually the flagship product from Cellucor, a Texas-based supplement company that is approximately 15 years old.

The firm has the following products under the Cellucor C4 name:

  • C4 Mass – strength and mass builder;
  • C4 50x – explosive intensifier with Excelsior, for lasting and quick energy;
  • C4 Ripped – it is a fat-cutting and explosive energy formula;
  • C4 Neuro – it is a cognitive performance and explosive energy supplement;
  • C4 Sport – it is a powerful pre-workout product, optimized for endurance, exercise, and focus;
  • Cellucor C4 Extreme – it promotes the endurance and energy to satisfy your fitness goals;
  • C4 Ultimate – it is the most powerful C4 ever created – designed for fitness enthusiasts who want no limits in the gym.


Theacrine & Tyrosine 

Theacrine is a chemical compound called an alkaloid which has been described as an altered version of caffeine. Tyrosine is a popular supplement that is used to improve attention, alertness, and focus.

When combined with caffeine, this pre-workout supplement works even more efficiently, providing synergistic effects that release adrenaline for a more extended workout and increases fatigue resistance and focus.

Caffeine Anhydrous

It helps to increase strength, performance, and concentration.

L-Arginine AAKG

It is a salt of the amino acid arginine and alpha-ketoglutaric acid. According to research, it helps to promote more concentration and resistance during weight and anaerobic exercise.

Because L-Arginine AAKG is depriving growing tumor cells of oxygen, it has been proven to provide anti-cancer activity. Furthermore, it enhances body functions like muscle oxygenation and blood flow, and it increases NO levels for more efficient nutrient delivery throughout the body.

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Creatine Nitrate

Creatine nitrate blends the benefits of dietary creatine and nitrates. It makes the muscles more likely to support weight training for long hours as it provides water retention in muscles. This leads to amazing post-workout effects as well.

Beta Alanine

It is a naturally occurring beta amino acid that increases muscular levels of carnosine. Carnosine is stored in cells and released in response to drops in pH. It comes in a 1.6-gram per C4 scoop.

CarnoSyn Beta-Alanine

It is designed to help reduce or delay the acidic burning feeling.


Some of its advantages include:

  • increased fat metabolism;
  • huge energy surge;
  • longer and more intense workouts;
  • increased muscle pump when working out.

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Side Effects

This pre-workout supplement is usually safe, however, some people can experience some side effects. Commonly reported side effects are:

  • chest pain;
  • vomiting;
  • kidney damage;
  • numbness in the lips, face, or extremities;
  • high blood pressure;
  • jitters;
  • anxiety;
  • cramps;
  • itching;
  • headaches;
  • trouble sleeping;
  • flushed and red skin.

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Bottom Line – NeuroCore vs C4

MuscleTech Neurocore is a concentrated pre-workout stimulant that offers intense pump, muscle, focus, strength, and energy. It costs about $1.30 per serving.

Cellucor C4 is one of the most popular pre-workout supplements and is used by hundreds of thousands of bodybuilders and athletes. It costs about $1 per serving.

In conclusion, the main difference between these effective pre-workout supplements is that Neurocore has double the amount of caffeine compared to C4.

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