Lipo-flavonoid (also Lipo-flavonoid Plus) is a dietary supplement formula created in 1961 by Miller, Smith, and Patch, which is claimed by the manufacturer Clarion Brands to improve circulation in the inner ear, as a means of combating ringing in the ears (tinnitus).
The supplement is designed to correct vitamin deficiencies caused by diet, improper absorption of minerals and vitamins and other factors.
While the exact nature of how Lipoflavonoid affects tinnitus is unknown, this supplement is thought to act on histamine (a natural compound produced by the body, also present in many foods), which plays a role in the circulation of blood in the ear canal tissues.
Tinnitus in the US
Approximately 10% of the United States adult population, or about 25 million Americans, has experienced tinnitus lasting at least 5 minutes in the past year. The average age of people in the United States with tinnitus is 57.
Tinnitus involves the annoying sensation of hearing sound when no external sound is present.
Occasionally, unclear music or voices are heard. Tinnitus is not a disease but a symptom that can result from a number of underlying causes. ”Ringing in the ears” can be perceived in one or both ears or in the head.
Note – the word tinnitus is of Latin origin, meaning “to ring or tinkle.”
It’s not clear exactly what causes this condition, however, it’s believed to be a problem with how the ear hears sounds and how the brain interprets them.
In a small number of patients, this ear disorder is a sign of a serious underlying medical condition.
There are two kinds of tinnitus.
- Objective tinnitus – this type can hear when your doctor does an examination. Nevertheless, this type of tinnitus is very rare and may be caused by a middle ear bone condition, a blood vessel problem, or muscle contractions.
- Subjective tinnitus – this type only you can hear the sounds. This is the most usual type of tinnitus. Subjective tinnitus can be caused by ear problems in your middle, outer, or inner ear. Moreover, it may be caused by problems with the part of your brain which interprets nerve signals as sound or the auditory nerves.
This supplement has not been approved by the Food and Drug Administration to treat, diagnose, cure, or prevent any disease.
The FDA does not regulate dietary supplements. Whereas drugs are considered unsafe until they are proven safe, supplements are the other way around.
Consumer testimonials claim that Lipo-flavonoid relieves the symptoms of tinnitus, but there is no good evidence that it is effective against hearing loss or tinnitus. In addition, there have not been any random controlled trials of Lipo-flavonoid for any purpose in the medical literature.
This supplement is composed principally of vitamin C, choline (a water-soluble nutrient), eriodictyol glycoside (also called lemon flavonoid), inositol (a type of sugar alcohol), a small amount of B vitamins and methionine (an essential amino acid).
You should not take this supplement with dairy products such as yogurt, cheese or milk. These dairy products may impede the body’s ability to absorb the vitamins provided by this supplement.
Side effects of Lipoflavonoid supplement
The dosage of the supplement is the most important information that the user should know about.
As this supplement’s side effects commonly arise from an overdose of the supplement, it becomes crucial to avoid even slight heavy dosage.
The most common side effects linked with this supplement could potentially cause stomach ache or bloody diarrhea, nausea or vomiting, hypersensitive reaction, headache, constipation, bad taste in the mouth, heartburn symptoms, or perhaps make the urine yellowish.
Serious side effects are very rare and commonly occur only when the multivitamins are combined with certain drugs, such as – isotretinoin (brand name Accutane – Acne treatment), tretinoin, or any non-steroidal anti-inflammatory drugs like ibuprofen (Motrin) or naproxen (Aleve).
Furthermore, all drugs designed to reduce water in the body should not be taken with this supplement. You may also experience signs of a severe allergic reaction, like – hives, unexplained rash, or sensation of swelling in your face or tongue.
It’s best to consult your healthcare specialist before adding this supplement to your diet, especially if you are taking other supplements, drugs or vitamins.
References https://www.ncbi.nlm.nih.gov/pubmed/2784987 https://www.sciencedaily.com/news/mind_brain/tinnitus/ http://bmjopen.bmj.com/content/7/10/e018465