Aubio vs Abreva – Comparison of Side Effects & Uses

Aubio Life Sciences

It is the brand name of a combination of allantoin and lidocaine.

Uses

This over-the-counter medicine is used for the temporary relief of itching and pain associated with cold sores and fever blisters.

Cold sores, also known as Herpes labialis, are small, painful, fluid-filled blisters which appear on the mouth, lips, or nose that are caused by a virus.

Cold sores should start to heal within 10 days, however, they may spread and be irritating or painful while they heal.

Herpes labialis generally are not serious, but the infection may be life-threatening for anyone who has AIDS or whose immune system has been curbed by medications or other disorders.

How To Use It

Gently clean the affected area before applying. Wash your hands before and after applying the cream.

Adults and children 2 years of age and older – apply to affected area not more than 3-4 times per day.

Note – always rub gently into affected area

Side Effects and Precautions

Common side effects may include:

  • mild tingling or cool feeling after applying the gel.

Rare side effects may include:

  • rash, hives, or itching.
  • breathing difficulties;
  • dizziness;
  • swelling of your lips, tongue, mouth, or face.

Contraindications

This medicine is not approved for use by children younger than 2 years old.

Alcohol

Avoid drinking alcoholic beverages while taking allantoin and lidocaine since alcohol use can substantially increase the risk of severe side effects.

Drug Interactions

There are no known drug interactions.

Pregnancy & Breastfeeding

It is not known whether allantoin and lidocaine pass into breast milk or if it could harm a nursing infant. Do not use this medicine antiviral without medical advice if you are breastfeeding an infant.

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It is not known whether allantoin and lidocaine will harm a developing fetus. Do not use this medicine without medical advice if you are pregnant.

Inactive Ingredients

This medicine contains the following inactive ingredients – Glycerin, Water (Aqua),  Sarracenia Stalk/Flower/Seed Extract (and) Sarracenia Purpurea Leaf/Stalk/ Flower/Seed Extract, Lavandula Angustifolia (Lavender) Flower Extract, Aloe Barbadensis Leaf Juice, Dipotassium Glycyrrhizate, Melissa Officinalis (Balm Mint) Extract, Ceramide AP, Ceramide EOP, Phytosphingosine, Carbomer, Cholesterol, Xanthan Gum, Ceramide NP,  Sodium Hydroxide, Hexylene Glycol, Sodium Lauroyl Lactylate, Caprylyl Glycol, Ethylhexylglycerin, and Phenoxyethanol.

Abreva

It is the brand name of a medication called docosanol that is part of a family of medications called antivirals.

This medication is produced by GlaxoSmithKline, a pharmaceutical company with the headquarters in London.

Mechanism of Action

It works by preventing the virus from entering the cells.

Contraindications

It is not approved for use by children younger than 12 years old.

Uses

This over the counter medication is used to treat fever blisters and cold sores in adults and children 12 years of age and older.

Note – it doesn’t cure herpes, however, it can speed up healing of sores and decrease symptoms.

Pregnancy & Breastfeeding

It is not known whether this antiviral medication will harm a developing fetus. Do not use this medication without medical advice if you are pregnant.

It is not known whether this antiviral medication passes into breast milk or if it could harm a nursing infant. Do not use this antiviral without medical advice if you are breastfeeding an infant.

Dosage

Important note – this medication should be applied at the very first sign of a cold sore, like – the tingle, bump, redness, or itch.

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Apply to affected area on face or lips 5 times a day.

Alcohol

Avoid drinking alcoholic beverages while taking this antiviral medication since alcohol use can substantially increase the risk of side effects.

Side Effects and Precautions

Common side effects may include:

  • headache;
  • dryness;
  • redness;
  • swelling.

Rare side effects may include:

  • rash, hives, or itching.
  • swelling of your lips, tongue, mouth, or face;
  • breathing difficulties.

Drug Interactions

You should tell your healthcare provider about all recreational, herbal, prescription, non-prescription, nutritional, or dietary drugs you are taking while on this antiviral. 

Bottom Line – Aubio vs Abreva

Aubio Life Sciences (active ingredients – allantoin and lidocaine) is a medicine that is used for the temporary relief of itching and pain associated with cold sores and fever blisters.

Abreva (active ingredient – docosanol) is an OTC medicine that is used to treat cold sore infections caused by the herpes simplex virus. Once absorbed through the skin, this antiviral works by blocking the virus which causes the cold sores from entering the healthy skin cells and growing.

References

https://www.ncbi.nlm.nih.gov/pubmed/25880800
http://www.jbc.org/content/57/2/379.full.pdf
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2036.2010.04278.x

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