Zioptan vs Lumigan For Glaucoma – Differences & Side Effects eyes

Zioptan

It is the brand name of a drug called tafluprost, that belongs to a group of drugs known as prostaglandin analogs.

This medication works by helping excess fluid drain from the eye, lowering the pressure in the eye.

Inactive ingredients – sodium dihydrogen, phosphate dihydrate, glycerol, hydrochloric acid and/or sodium hydroxide, disodium edetate, and polysorbate 80.

Uses

This prescription medication is used to treat ocular hypertension or open-angle glaucoma.

Open-angle glaucoma, the most common form of glaucoma, accounts for approximately 90 percent of all glaucoma cases. Open-angle glaucoma usually happens to people over 50.

Dosage

The usual recommended dose is 1 drop of medication in the affected eye(s) once per day in the evening.

Notes – if you use other medicines in your eye, wait 10 minutes between using tafluprost and your other eye medicines. Also, it may not work as well if you use it more than 1 time each evening.

Side Effects and Precautions

Common side effects may include:

  • a cough;
  • redness or itching of your eye;
  • urinary tract infection;
  • cataract formation;
  • common cold;
  • dry eye;
  • headaches;
  • blurred vision;
  • eye pain.

Rare side effects may include:

  • severe redness of the eyes after using the medicine;
  • increased sensitivity to light;
  • itchy or watery eyes;
  • eye pain or redness.

Contraindications

To be sure that this medication is safe for you, tell your healthcare provider if you:

  • have any other medical problems;
  • are using any other eye medicines;
  • have or have had eye problems.

Drug Interactionst

It may negatively interact with other medications, especially:

  • Rescula (unoprostone ophthalmic);
  • bimatoprost ophthalmic;
  • Vyzulta (latanoprostene bunod ophthalmic);
  • unoprostone ophthalmic;
  • latanoprostene bunod ophthalmic.

Pregnancy & Breastfeeding

It is not known exactly if this medication passes into the breast milk or if it could negatively affect a breastfed baby. Tell your healthcare provider that you are breastfeeding a baby before using this medication.

It is not known precisely if this medication will harm a developing fetus. Tell your doctor that you are pregnant or plan to become pregnant before using this medication.

Lumigan

Image credit – https://commons.wikimedia.org/wiki/File:Lumigan.jpg

It is the brand name of a medication called bimatoprost, that is part of a family of drugs known as prostaglandin analogs.

This medication works by regulating the flow of fluid within the eye in order to maintain a healthy pressure.

It is manufactured by Allergan, Inc, a pharmaceutical company focused on neurosciences and eye care. The U.S. Food and Drug Administration originally approved this prostaglandin analog in 2001.

Uses

It is used to treat certain types of glaucoma and other causes of high pressure inside the eye.

In addition, this medication is used to improve length, fullness, and color of the eyelashes in people with hypotrichosis, a condition which affects hair growth.

Dosage

This medication comes in eye drop form. The usual recommended dosage is one drop in the affected eye once a day in the evening.

Notes – if you wear contact lenses, it is suggested to remove them before applying this eye drop medication, and then wait approximately 15 minutes before putting them back in your eyes.

You should apply this medication at least 5 minutes before or after using any other topical eye medications.

Contraindications

To be sure that this medication is safe for you, tell your healthcare provider if:

  • you have kidney problems;
  • you have had an inflammation of the eye;
  • you wear contact lenses;
  • you have had a viral infection;
  • you have had a cataract surgery in the past;
  • you have or have had low heart rate;
  • you have or have had any problems with the cornea;
  • you have or have had low blood pressure;
  • you have liver problems;
  • you have a dry eye;
  • you have any breathing problems.

Side Effects and Precautions

Common side effects may include:

  • the growth of eyelashes;
  • dry eyes;
  • eye irritation;
  • itching of the eyes;
  • eye redness;
  • eyelash darkening;
  • reversible darkening of the skin around the eyes.

Less common side effects may include:

  • swelling in or around the eye;
  • vision changes;
  • redness of the eyelids;
  • discharge from the eye;
  • increased sensitivity to light.

Drug Interactions

It may negatively interact with other medications, especially:

  • travoprost ophthalmic;
  • bimatoprost topical;
  • mononessa;
  • Rescula (unoprostone ophthalmic);
  • Izba (travoprost ophthalmic);
  • unoprostone ophthalmic;
  • latanoprost ophthalmic;
  • Zioptan (tafluprost ophthalmic);
  • latanoprostene bunod ophthalmic;
  • Xalatan (latanoprost ophthalmic);
  • sprintec;
  • Latisse (bimatoprost topical).

Pregnancy & Breastfeeding

It is not known precisely if this medication will harm a developing fetus. Tell your doctor that you are pregnant or plan to become pregnant before using this medication.

It is not known exactly if this medication passes into your breast milk or if it could negatively affect a breastfed baby. Tell your healthcare provider that you are breastfeeding a baby before using this medication.

Bottom Line – Zioptan vs Lumigan

Zioptan (active ingredient – tafluprost) is a medication that is indicated for reducing elevated intraocular pressure in people with open-angle glaucoma or ocular hypertension.

Lumigan (active ingredient – bimatoprost) is a medication that is used to treat certain types of glaucoma and other causes of high pressure inside the eye. It works by increasing the amount of fluid which drains from the eye.

In conclusion, both medications are effective for the treatment of glaucoma but they have different active ingredients. They both have very few side effects.

References

https://www.aao.org/eyenet/article/landmark-glaucoma-studies-key-findings-treatment-l
https://www.ncbi.nlm.nih.gov/pubmed/12698048

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