Tussin vs Robitussin – Comparison Between Uses & Side Effects

Tussin CF

It is the brand name of a combination of guaifenesin, dextromethorphan, and phenylephrine.

Guaifenesin, also known as guaiphenesin, is an expectorant that helps loosen congestion in the chest and throat, making it substantially easier to cough out through the mouth.

Dextromethorphan (chemically related to codeine) is a cough suppressant that affects the signals in the brain which trigger the cough reflex.

Phenylephrine is an α-receptor agonist without β-agonist activity which shrinks blood vessels in the nasal passages.

Uses

This medication is used to treat stuffy nose, cough, sinus congestion and chest congestion caused by the common cold, allergies, or the flu.

Dosage

The usual recommended dose for adults and children 12 years and over is 10 mL every 4 hours.

Notes – do not give this medication to a child younger than 12 years old. Do not take this medication for longer than 7 days in a row.

Side Effects

Common side effects may include:

  • feeling restless, nervous, or irritable;
  • diarrhea;
  • sleep problems (insomnia);
  • drowsiness;
  • dizziness.

Rare side effects may include:

  • fever;
  • fast heart rate;
  • seizure;
  • uneven heartbeats;
  • a feeling like you might pass out;
  • mood changes;
  • blurred vision;
  • chest pain;
  • buzzing in your ears;
  • severe dizziness;
  • anxiety;
  • a severe headache.

Precautions

To be sure that this medication is safe for you, tell your doctor if you have:

  • epilepsy or other seizure disorder;
  • type 2 diabetes;
  • pheochromocytoma (an adrenal gland tumor);
  • glaucoma;
  • a cough caused by emphysema or chronic bronchitis;
  • urination problems;
  • a cough with mucus;
  • enlarged prostate.

Contraindications

Do not take this medication if you are now taking a prescription monoamine oxidase inhibitor, or for 2 weeks after stopping the monoamine oxidase inhibitor drug.

Alcoholalcohol

There may be a negative interaction between this medication and alcohol use.

Drug Interactionsdrugs pills

It may negatively interact with other medications, especially:

  • doxepin (Sinequan);
  • amitriptyline (Elavil, Limbitrol);
  • duloxetine (Cymbalta);
  • tylenol;
  • citalopram (Celexa);
  • nortriptyline (Pamelor);
  • escitalopram (Lexapro);
  • sertraline (Zoloft);
  • fluoxetine (Prozac, Selfemra, Symbyax);
  • venlafaxine (Effexor);
  • fluvoxamine (Luvox);
  • vilazodone (Viibryd);
  • paroxetine (Paxil);
  • arnuity ellipta;
  • trazodone (Oleptro).

Pregnancy & Breastfeeding

It is not known exactly whether this medication will harm a developing fetus. Do not use this medication without a healthcare professional’s advice if you are pregnant or plan to become pregnant.

It is not known precisely whether this medication passes into breast milk or if it could negatively affect a nursing baby. Do not use this medication without a healthcare professional’s advice if you are breastfeeding an infant.

Abuse

Taking too much dextromethorphan can lead to loss of motor control, hallucinations, and out-of-body sensations, making this drug a target for abuse. Overdosing on this medication may pose the following health risks:

  • coma;
  • slow breathing;
  • nausea;
  • muscle twitching;
  • paranoia;
  • blurred vision;
  • seizures;
  • gastrointestinal spasms;
  • high blood pressure;
  • feeling drowsy;
  • constipation;
  • rapid heartbeat.

Robitussin Cough & Cold CF

Image credit – https://www.flickr.com/photos/39160147@N03/16221108012

It is the brand name of a combination of phenylephrine, dextromethorphan, and guaifenesin.

Phenylephrine is an α-receptor agonist without β-agonist activity which shrinks blood vessels in the nasal passages.

Dextromethorphan (chemically related to codeine) is a cough suppressant that affects the signals in the brain which trigger the cough reflex.

Guaifenesin, also known as guaiphenesin, is an expectorant that helps loosen congestion in the chest and throat, making it substantially easier to cough out through the mouth.

Uses

This medication is used to treat sinus congestion, cough, stuffy nose, and chest congestion caused by the common cold, allergies, or the flu.

Dosage

The usual recommended dose for adults and children 12 years and over is 10 mL every 4 hours.

Notes – do not give this medication to a child younger than 12 years old. Do not take this medication for longer than 7 days in a row.

Contraindications

It is not recommended to use this medication:

  • if you have diabetes;
  • if you have high blood pressure;
  • if you have a thyroid disease;
  • if you are 12 years old or younger;
  • if you ever had Stevens-Johnson syndrome;
  • if you are taking monoamine oxidase inhibitors.

Side Effects

Common side effects may include:

  • nausea;
  • diarrhea;
  • dry mouth;
  • headaches;
  • upset stomach;
  • dizziness.

Less common side effects may include:

  • severe dizziness;
  • shallow breathing;
  • hallucinations;
  • itching;
  • weak pulse;
  • tingling under your skin;
  • slow heart rate;
  • skin rash;
  • unusual behavior;
  • urinating less than usual;
  • constipation;
  • drowsiness;
  • confusion;
  • unusual thoughts.

Alcohol

Drinking alcoholic beverages while taking this medication can considerably increase certain side effects.

Drug Interactions

It may negatively interact with other medications, especially:

  • ibuprofen;
  • lisinopril;
  • omeprazole;
  • acetaminophen;
  • gabapentin;
  • Tylenol (acetaminophen);
  • prednisone;
  • albuterol;
  • aspirin;
  • Zyrtec (cetirizine).

Pregnancy & Breastfeeding

It is not known exactly whether this medication will harm an unborn baby. Do not use this drug without a healthcare provider’s advice if you are pregnant or plan to fall pregnant.

It is not known precisely whether this medication passes into breast milk or if it could negatively affect a nursing infant. Do not use this drug without a healthcare provider’s advice if you are breast-feeding a baby.

Bottom Line – Tussin vs Robitussin

Tussin CF (active ingredients – phenylephrine, dextromethorphan, and guaifenesin) is a medication that is used to temporarily treat a cough, chest congestion, stuffy nose, and sinus congestion caused by the flu, allergies, the common cold, hay fever, or other breathing illnesses.

Robitussin Cough & Cold CF (active ingredients – phenylephrine, dextromethorphan, and guaifenesin) is a combination medicine that is used to treat sinus congestion, a cough, stuffy nose, and chest congestion caused by the common cold, allergies, or the flu.

In conclusion, both medications have the same active ingredients. The differences lie in the brand name, price, and inactive ingredients.

References

http://journal.chestnet.org/article/S0096-0217(16)30909-8/fulltext
https://www.sciencedaily.com/releases/2007/11/071107160159.htm
https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0010512/

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